Shine Jacob, PMP


Sr.Program Manager, ESAC

Location: Rockville, MD


Certified Scrum Professional
Certified ScrumMaster



Fifteen plus years full life-cycle software development experience; Five years of leadership and technical management expertise. Experienced in managing full Systems Development Life Cycle for various bioinformatics projects. Led cross-functional teams with diverse background in the areas of translational research, pre-clinical, clinical, genomics and proteomics. Hands-on lead for Application development, Database Architecture & development, Document management system, Data Conversion, Data warehousing, LIMS and Life Science Data Integration.

Selected Employment History


ESAC Inc (Self Employed), Rockville, MD, 2006 – Present

Client: NCI CBIIT (caBIG)     Role: Program Manager

Technical PM responsible for requirement, analysis and development of the next-generation translational research platform (caIntegrator) to integrate clinical, array (gene expression, SNP etc), image annotations and various other data source, query and to analyze using visualization tools (like GenePattern). Worked with the Product Manager to scope the vision, build the team and managed development.

  Project Manager for various cancer study data portals (brain tumor, breast cancer etc) managing multiple releases in a matrix, resource sharing, environment. Data manager accountable for data acquisition, pre-processing, loading, validation and customer satisfaction.  

 Project Manager for Integrative Cancer Research (ICR) community workspace within caBIG program for several life-science products. Managed customer requirements, tool adoption programs and user expectations. Helped with identifying, processing and granting of work for NCI supported cancer centers. Directed open source development for the tool adoption program.

 Technology and process used includes RUP, Agile, EA, Use-Case, UML, Java, Hibernate, Struts, MySQL, Oracle, NetCDF, SVN, and GFroge. Responsible for resource management and budgeting.

 Client: Fannie Mae   Role: Project Lead/Manager

 Managed a team of developers, business analysts and DBA’s for a complex financial data conversion project. Developed a strategy for conversion, designed the technical architecture, led the business analysis, led the development effort, ensured quality and achieved business sign-off.

Celera Genomics, Rockville, MD, 2001 – 2006      Sr. Software Engineer II/Project Lead

Managed cross functional team of managers, scientists, technologists and programmers in successfully procuring, customizing, implementing and training of the Enterprise Document Management System for pre-clinical studies and IND filing.  

Managed software team for conducting the requirement analysis, design, development, testing and support for LIMS (Lab Information Management System) for proteomics and genomics lab. Worked with multiple departments (Cell Biology, protein chemistry, Mass Spec) to reach consensus and successful implementation.

Lead Database Architect for various informatics solutions including Biomarker application for curating and analyzing gene expression data measured with real-time PCR, designing a data warehouse and ETL process for downstream data analysis from the LAB generated data.

Educated colleagues on FDA’s 21 CFR Part 11 compliance.Initiated talks with various inter-company business heads and developed new business opportunities for informatics. Evaluated and recommended supporting systems, managed relationship between IT, Informatics, external vendors, internal departments (finance, procurement) and end- users.


MS, Information System and Technology, Johns Hopkins, 2003


BS, Computer Science, University of Mangalore, India, 1993



 Project Management, Use Case Management, RUP, Scrum/Agile/OpenUP

 Database – Certified Sybase DBA and Oracle PL/SQL developer

 Java/J2EE, Hibernate, UML, RUP, Shell, PERL